• Pharmacy Hours
  • Monday - Friday: 8am - 6pm
  • Saturday: 9am - 1:30pm
  • Sunday: Closed
  • Follow Us
  •  

Drug Reference

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Click a letter to see a list of items beginning with that letter.

Desvenlafaxine Succinate Oral tablet, extended-release

Additional titles for this drug

Pristiq 100mg Extended-Release Tablet, Pristiq 50mg Extended-Release Tablet

What is this medicine?

DESVENLAFAXINE (des VEN la FAX een) is used to treat depression.

How should I use this medicine?

Take this medicine by mouth with a drink of water. Do not crush, cut or chew. Follow the directions on the prescription label. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking it except on your prescriber's advice.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • hallucination, loss of contact with reality

  • mania (over-active behavior)

  • increase in blood pressure

  • redness, blistering, peeling or loosening of the skin, including inside the mouth

  • seizures

  • sexual difficulties (abnormal ejaculation or orgasm)

  • unusual bleeding or bruising

  • vomiting

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • constipation

  • difficulty sleeping

  • dizziness, drowsiness

  • dry mouth

  • increased sweating

  • loss of appetite

  • nausea

  • tremor

What may interact with this medicine?

Do not take this medicine with any of the following medications:

  • duloxetine

  • linezolid

  • MAOIs like Azilect, Carbex, Eldepryl, Marplan, Nardil, and Parnate

  • methylene blue

  • venlafaxine

This medicine may also interact with the following medications:

  • alcohol

  • amphetamine

  • aspirin and aspirin-like medicines

  • certain migraine headache medicines (almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, sumatriptan, zolmitriptan)

  • dexfenfluramine or fenfluramine

  • dextroamphetamine

  • furazolidone

  • isoniazid

  • lithium

  • medicines for heart rhythm or blood pressure

  • medicines that treat or prevent blood clots like warfarin, enoxaparin, and dalteparin

  • methylphenidate

  • metoclopramide

  • NSAIDS, medicines for pain and inflammation, like ibuprofen or naproxen

  • pentazocine

  • phentermine

  • procarbazine

  • protriptyline

  • sibutramine

  • St. John's wort, Hypericum perforatum

  • tramadol

  • tryptophan

  • zolpidem

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • high blood pressure

  • kidney disease

  • liver disease

  • mania or bipolar disorder

  • suicidal thoughts or a previous suicide attempt

  • an unusual reaction to desvenlafaxine, venlafaxine, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress. You may have to take this medicine for several weeks before you feel better.

If you have been taking this medicine for some time, do not suddenly stop taking it. You must gradually reduce the dose to avoid side effects. Ask your prescriber or health care professional for advice.

Patients and their families should watch out for worsening depression or thoughts of suicide. Also watch out for sudden or severe changes in feelings such as feeling anxious, agitated, panicky, irritable, hostile, aggressive, impulsive, severely restless, overly excited and hyperactive, or not being able to sleep. If this happens, especially at the beginning of antidepressant treatment or after a change in dose, call your health care professional.

This medicine can cause an increase in blood pressure. Check with your doctor or health care professional; you may be able to measure your own blood pressure and pulse. Find out what your blood pressure and heart rate should be and what steps you should take if they increase.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may increase dizziness or drowsiness; avoid alcoholic drinks.

This medicine can make your mouth dry. Chewing sugarless gum, sucking hard candy and drinking plenty of water will help.

No Content Found.