Palifermin (E. coli) Solution for injection

Additional titles for this drug

What is this medicine?

PALIFERMIN (pal ee FER min) is a man-made form of a natural growth factor. It is used to treat and to prevent severe mouth sores in patients with blood-related cancers receiving chemotherapy and/or radiation therapy.

How should I use this medicine?

This medicine is for injection into a vein. It is given by a health care professional in a hospital or clinic setting.

Talk to your pediatrician regarding the use of this medicine in children. This medicine is not approved for use in children.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

• allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

• burning, tingling in or around the mouth

• fever

• high blood pressure

• joint pain

• swelling of the hands or feet

• thickening of the tongue

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

• change in tongue color

• changes in taste

• stomach upset

What may interact with this medicine?

• medicines to treat cancer

What if I miss a dose?

It is important not to miss your dose. Call your doctor or health care professional if you are unable to keep an appointment.

Where should I keep my medicine?

This drug is given in a hospital or clinic and will not be stored at home.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

• an unusual or allergic reaction to palifermin, E. coli protein, other medicines, foods, dyes, or preservatives

• pregnant or trying to get pregnant

• breast-feeding

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress.

Do not use this medicine if you have a cancer that is not a blood-related cancer. This medicine may cause other cancers to grow.