Drug Reference

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Gemtuzumab Ozogamicin (Human)(Murine) Solution for injection

Additional titles for this drug

Mylotarg 5mg Powder for Injection

What is this medicine?

GEMTUZUMAB OZOGAMICIN (jem TOOZ oo mab OH zoe ga MYE sin) is a monoclonal antibody. This medicine changes the way the body's immune system works. By interfering with a specific protein, this medicine can stop cancer cell growth. It is used to treat acute myelogenous leukemia (AML).

How should I use this medicine?

This medicine is for infusion into a vein. It is administered in a hospital or clinic by a specially trained health care professional.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • low blood counts - this medicine may decrease the number of white blood cells, red blood cells and platelets. You may be at increased risk for infections and bleeding.

  • signs of infection - fever or chills, cough, sore throat, pain or difficulty passing urine

  • signs of decreased platelets or bleeding - bruising, pinpoint red spots on the skin, black, tarry stools, blood in the urine

  • signs of decreased red blood cells - unusually weak or tired, fainting spells, lightheadedness

  • breathing problems

  • fast, irregular heartbeat

  • feeling faint or lightheaded, falls

  • low blood pressure

  • mouth sores

  • right upper belly pain

  • stomach pain

  • sudden weight gain

  • trouble passing urine or change in the amount of urine

  • vomiting

Side effects that usually do not require medical attention (report to your doctor or other health care professional if they continue or are bothersome):

  • constipation

  • diarrhea

  • headache

  • loss of appetite

  • muscle aches

  • nausea

What may interact with this medicine?

  • vaccines

Talk to your doctor or health care professional before taking any of these medicines:

  • acetaminophen

  • aspirin

  • ibuprofen

  • ketoprofen

  • naproxen

What if I miss a dose?

It is important not to miss a dose. Call your doctor or health care professional if you are unable to keep an appointment.

Where should I keep my medicine?

This drug is given in a hospital or clinic and will not be stored at home.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • blood disorders

  • infection (especially a virus infection such as chickenpox, cold sores, or herpes)

  • low blood counts

  • lung or breathing disease, like asthma

  • liver disease

  • an unusual or allergic reaction to gemtuzumab ozogamicin, mouse proteins, other chemotherapy, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

This drug may make you feel generally unwell. This is not uncommon, as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your doctor tells you to stop.

Drink fluids as directed while you are taking this medicine to prevent kidney damage.

Call your doctor or health care professional for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu. Do not treat yourself. This drug decreases your body's ability to fight infections. Try to avoid being around people who are sick.

This medicine may increase your risk to bruise or bleed. Call your doctor or health care professional if you notice any unusual bleeding.

Be careful brushing and flossing your teeth or using a toothpick because you may get an infection or bleed more easily. If you have any dental work done, tell your dentist you are receiving this medicine.

Avoid taking products that contain aspirin, acetaminophen, ibuprofen, naproxen, or ketoprofen unless instructed by your doctor. These medicines may hide a fever.

Do not become pregnant while taking this medicine. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine.

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Medicap Pharmacy
400 1st Avenue West
Newton, IA 50208

Ph. 641-792-3528
Fx. 641-792-3526

Pharmacy Hours:

Mon-Fri: 8:30am-6:30pm
Sat: 9:00am-1:30pm
Sun: Closed

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